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Unsecured Synthetic Royalties May Be Returning

Article June 11, 2026

Law360

The recent HCRx-Oncoceutics royalty monetization, following last year's Royalty Pharma-Revolution Medicines synthetic royalty financing, signals that investors are again willing to accept unsecured synthetic royalty exposure under the right circumstances. These deals mark a notable shift in a market that had largely moved away from unsecured structures after a multiyear market freeze triggered by a 2022 Mallinckrodt bankruptcy decision.

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